Polymeric Adhesive Matrix with Salified Carboxylic Groups for Transdermal Use
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United States of America Patent
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app pub date -
Jul 6, 2005
filing date -
Aug 6, 2004
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Abstract
Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0.degree. C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
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