Use of Arginase in Combination with 5FU and Other Compounds for Treatment of Human Malignancies

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United States of America Patent

APP PUB NO 20080292609A1
SERIAL NO

11751050

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Abstract

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The present invention provides a method for treating cancer in a human patient by reducing the physiological arginine levels to below 10 .mu.M in combination with administering an anti-neoplastic compound. The present invention also provides a pharmaceutical composition comprising an arginine reducing compound, such as pegylated human arginase I, and an anti-neoplastic compound, such as 5-fluorouracil, for the treatment of malignancies in a human patient.

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Patent Owner(s)

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BIO-CANCER TREATMENT INTERNATIONAL LIMITEDHONG KONG

International Classification(s)

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  • 2007 Application Filing Year
  • A61K Class
  • 9805 Applications Filed
  • 5595 Patents Issued To-Date
  • 57.07 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2007200820092010201120122013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Ning Man Hong Kong, CN 11 26
Leung, Yun Chung Hong Kong, CN 19 33
Lo, Wai Hung Hong Kong, CN 7 15

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  • 2 Citation Count
  • A61K Class
  • 11.28 % this patent is cited more than
  • 17 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges43920207043221518650412213133001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +01002003004005006007008009001000110012001300140015001600170018001900200021002200

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