Biologically Active Compounds with Anti-Angiogenic Properties

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United States of America Patent

APP PUB NO 20080280837A1
SERIAL NO

11547343

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for inhibiting angiogenesis in a subject comprising administering to the subject at least one compound of General Formula (I), wherein the ring or any chiral center(s) may be of any configuration; Z is sulphur, oxygen, CH2, C(O), C(O)HN, NH, NRA or hydrogen, in the case where Z is hydrogen then R1 is not present, RA is selected from the set defined for R1 to R5, X and X' are independently oxygen or nitrogen providing that at least one X of General Formula (I) is nitrogen, X or X' may also combine independently with one of R1 to R5 to form an azide, R1 to R5 are independently selected from the following definition which includes but is not limited to H or an alkyl, acyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl substituent of 1 to 20 atoms, which is optionally substituted, and can be branched or linear, and R6 and R7 are hydrogen, or may combine to form a carbonyl function.

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Patent Owner(s)

Patent OwnerAddress
ALCHEMIA LTDBRISBANE QLD 4113

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Bernd New Farm, AU 41 311
Condie, Glenn Kagaroo Point, AU 2 3
Halliday, Judy Chappel Hill, AU 4 11
McKeveney, Declan Kagaroo Point, AU 3 7
Meutermans, Wim Toowong, AU 17 63
Muldoon, Craig Eight Mile Plains, AU 7 29
Premraj, Rajaratnam Eight Mile Plains, AU 3 7
Ramsdale, Tracie E Sunnybank, AU 6 21
Tometzki, Gerald Manly West, AU 8 37
Zuegg, Johannes Wynnum, AU 10 14

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