Assays for Detecting Hiv-1 Tat Protein in Hiv-1 Infection
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United States of America Patent
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Issued Date -
Nov 13, 2008
app pub date -
Feb 13, 2006
filing date -
Feb 15, 2005
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Abandoned
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Abstract
A method for detecting or measuring HIV-1 Transactivating (Tat) protein in a biological sample comprising contacting the biological sample with an amount of a basic protein effective to reduce interference with binding between anti-HIV-1 Tat Epitope 2 ligand and Tat that is caused by acidic components within the sample or reagents. A more accurate detection and measurement of the amount of HIV-1 Tat in the sample is obtained by binding between the anti-Epitope 2 antibody and the Tat in the sample when the interference is neutralized. A diagnostic kit for use in practicing the method contains these components.
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