Treatment of androgen-deprivation induced osteoporosis
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United States of America Patent
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Issued Date -
Oct 9, 2008
app pub date -
Feb 22, 2008
filing date -
Nov 29, 2001
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Abandoned
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Abstract
This invention provides a method of treating androgen-deprivation induced osteoporosis, bone fractures or loss of bone mineral density (BMD) in a male human subject suffering from prostate cancer, wherein the subject has a precipitous decline in androgen levels, by administering a pharmaceutical composition comprising Toremifene or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof, to the subject, wherein the method increases bone density without increasing androgen and specifically testosterone levels in the subject.
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