POLYPEPTIDES HAVING A TRIGGERING NK ACTIVITY AND BIOLOGICAL APPLICATIONS

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United States of America Patent

SERIAL NO

11861511

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Abstract

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The invention relates to polypeptides having a triggering NK activity and an amino acid sequence that is at least 80% identical over its entire length to the polypeptide having SEQ ID NO: 1, and any immunogenic fragments thereof, as well as to the polyclonal and monoclonal antibodies directed against said polypeptides, and immuno-reactive fragments thereof. Application for detecting NK cells in a sample, for their removal from a sample or for enrichment of NK cells, and for NK cell natural cytotoxicity regulation.

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Patent Owner(s)

Patent OwnerAddress
INNATE PHARMA S A13009 MARSEILLE
UNIVERSITA DI GENOVAVIA L B ALBERTI 2 GENOVA 16132

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biassoni, Roberto Genova, IT 9 17
Bottino, Cristina Genova, IT 8 17
Moretta, Alessandro Genova, IT 32 304

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