DIFFERENTIALLY EXPRESSED GENES INVOLVED IN ANGIOGENESIS, THE POLYPEPTIDES ENCODED THEREBY, AND METHODS OF USING THE SAME

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United States of America Patent

APP PUB NO 20080241835A1
SERIAL NO

11927609

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Abstract

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The present invention is directed to nucleic acid sequences and the polypeptides encoded thereby that are differentially expressed in angiogenesis. Also provided are methods for stimulating or inhibiting angiogenesis in mammals, including humans. Pharmaceutical compositions based on polypeptides, agonists, or antagonists thereto are also provided. Additionally, the invention also provides methods for diagnosing and treating angiogenic disorders including, but not limited to, wound healing and cancer.

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GENENTECH INCCALIFORNIA USA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gerritsen, Mary San Mateo, CA 4 30
Mehraban, Fuad Trumbull, CT 5 57
Rastelli, Luca Guilford, CT 119 937

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