NOVEL HUMAN GENE FUNCTIONALLY RELATED TO DYSLEXIA

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United States of America Patent

APP PUB NO 20080241178A1
SERIAL NO

12045602

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Abstract

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The present invention describes a novel human gene, DYXC1, which is functionally related to dyslexia. DYXC1 gene encodes a 420-amino acid residue protein. DYXC1 is expressed in several tissues, including the brain, and is localized in the nucleus. In addition, four single nucleotide polymorphisms (SNPs) in DYXC1 mRNA have been characterized in this invention. The invention provides diagnostic methods and materials for analysing allelic variation in DYSC1 gene. This invention also provides polypeptides encoded by DYXC1 gene and antibodies binding to said polypeptides.

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Patent Owner(s)

Patent OwnerAddress
LICENTIA LTDTUKHOLMANKATU 8 A HELSINKI FI-00290

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kaminen, Nina Helsinki, FI 3 3
KERE, Juha Stockholm, SE 10 22
Nopola-Hemmi, Jaana Helsinki, FI 3 3
Taipale, Mikko Heidelberg, DE 7 12

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