Polymeric Micelle Type Mri Imaging Agent
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United States of America Patent
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Issued Date -
Oct 2, 2008
app pub date -
Jan 6, 2005
filing date -
Jul 5, 2004
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Abandoned
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Abstract
A contrast agent for magnetic resonance imaging which stably circulates in the blood for a long period and which targets solid tumors, with which clear images of cancers may be obtained is disclosed. The contrast agent for magnetic resonance imaging comprises as an effective ingredient a polymeric micelle having gadolinium (Gd) atoms in an inner core and an outer shell including hydrophilic polymer chain segments, which micelle is delivered to a tissue(s) and/or site(s) of solid tumor(s) in vivo, whose micellar structure is dissociated after being accumulated in the tissue(s) and/or site(s).
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