Preparation with Elevated Content
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United States of America Patent
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Issued Date -
Sep 25, 2008
app pub date -
Mar 23, 2005
filing date -
Mar 24, 2004
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A composition for oral use, which contains a drug compound (in particular, a hardly water soluble or water-insoluble drug compound) in an elevated amount and is excellent in the absorbability of the drug compound via the digestive tract, is produced by dispersing the drug compound in an oily base and a surfactant in an amount exceeding the solubility thereof in the mixture of the oily base with the surfactant under heating, adding a polar solvent which serves as a poor solvent for the drug compound to the thus obtained dispersion, and heating the mixture to give a transparent liquid composition. Further, the obtained composition is encapsulated to give a capsule preparation.
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