N3-Pyridyl-Thiamine And Its Use In Cancer Treatments

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United States of America Patent

APP PUB NO 20080234304A1
SERIAL NO

10594191

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Abstract

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The invention provides methods using N3-pyridyl-thiamine compounds and pharmaceutical compositions comprising N3-pyridyl-thiamine, which are especially useful for preventing or reducing tumor growth in vivo. The invention is also directed to the benefits of reducing thiamine concentrations, e.g., by means of a thiamine reduced diet, as an effective step in a therapeutic regime for patients treated with N3-pyridyl-thiamine.

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Patent Owner(s)

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AVEO PHARMACEUTICALS INC75 SIDNEY STREET FOURTH FLOOR CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gyuris, Jeno Lincoln, MA 63 604
Han, May Brookline, MA 15 121
O'Hagan, Ronan C Arlington, MA 4 1
Robinson, Murray Boston, MA 21 61
Weiler, Solly Newton, MA 17 213

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