USE OF BIOMOLECULAR TARGETS IN THE TREATMENT AND VISUALIZATION OF TUMORS

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United States of America Patent

APP PUB NO 20080226646A1
SERIAL NO

12045448

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the use of a protein that is differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as a biomolecular target for tumor treatment therapies. The protein is also expressed in tissues from adenocarcinoma, non-melanoma, and renal carcinoma cells. Immunotherapeutic and immunoimaging agents that specifically bind to an identified brain tumor target protein are provided. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.

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Patent Owner(s)

Patent OwnerAddress
MEDAREX INCROUTE 206 & PROVINCE LINE RD PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chin, Daniel J US 13 334
Foehr, Erik US 12 233
Gonzalez-Zulueta, Mirella US 11 107
Mueller, Sabine US 7 86

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