Novel Resinate Complex of S-Clopidogrel and Production Method Thereof
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United States of America Patent
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Issued Date -
Sep 18, 2008
app pub date -
Aug 24, 2006
filing date -
Sep 21, 2005
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Abstract
The present invention is a novel resinate complex of (+)-clopidogrel optical isomer, wherein the (+)-clopidogrel isomer is bounded to a water-soluble cation exchange resin having sulfonic acid groups. The novel resinate complex has recognized some advantages in that (1) its chemical structure is stable, and (2) it can be formulated into a solid form that may provide taste-masking capabilities associated with bitter drugs (e.g., strong irritation, bitterness and sour taste), thus requiring no drink of water.
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