Methods of Treating Chronic Inflammatory Diseases Using a GM-CSF Antagonist
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United States of America Patent
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Issued Date -
Aug 28, 2008
app pub date -
Nov 21, 2007
filing date -
Nov 21, 2006
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Abstract
The invention is based on the discovery that GM-CSF antagonists can be used for the treatment of chronic inflammatory disease, such as rheumatoid arthritis. Accordingly, the invention provides methods of administering a GM-CSF antagonist, e.g., a GM-CSF antibody, and an anti-folate compounds, e.g., methotrexate, to a patient that has RA and pharmaceutical compositions comprising such antagonists.
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