Compositions and methods utilizing DNA polymerases
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United States of America Patent
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Issued Date -
Aug 21, 2008
app pub date -
Dec 22, 2006
filing date -
Oct 29, 1999
priority date (Note) -
Abandoned
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Abstract
The invention features a novel isolated Family B DNA polymerase, a Thermococcus polymerase JDF-3, and mutant recombinant forms thereof. Mutant polymerases of the invention are deficient in 3' to 5' exonuclease activity and/or exhibit reduced discrimination against non-conventional nucleotides relative to the wild-type form of the polymerase.
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