Transgenic Animals and Methods of Making Recombinant Antibodies
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United States of America Patent
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Issued Date -
Aug 14, 2008
app pub date -
Apr 28, 2006
filing date -
Apr 29, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention concerns a means for obtaining cells which produce human, humanized or chimeric antibodies in commercially useful quantities. The invention permits high antibody producer cells to be selected and isolated from animals for use in culture to produce antibodies. The invention also provides methods for the affinity maturation of human, humanized or chimeric immunoglobulins.
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