SEQUENCING OF OLIGONUCLEOTIDES BY MASS SPECTROMETRY
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United States of America Patent
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Issued Date -
Aug 7, 2008
app pub date -
Nov 26, 2007
filing date -
Nov 29, 2006
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Abandoned
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Abstract
A method of sequencing nucleic acids is provided which uses ion ratios derived by measuring ion abundance at both a high and low collision energy. These ion rations are useful for assigning charge states to product ions, as well as for sequencing the terminal sequences. In addition, methods for using internal ions to sequence the nucleic acids are described.
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