Compositions and methods for detecting, preventing and treating seizures and seizure related disorders

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United States of America Patent

APP PUB NO 20080188461A1
SERIAL NO

11823971

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compositions and methods for the detecting, preventing, treating, and empirically investigating seizures and seizure related disorders (e.g., West syndrome, TSC, childhood absence epilepsy, benign focal epilepsies of childhood, juvenile myoclonic epilepsy (JME), temperol lobe epilepsy, frontal lobe epilepsy, Lennox-Gastaut syndrome, occipital lobe epilepsy). In particular, the present invention provides compositions and methods for detecting, treating, preventing and empirical investigating seizures and seizure related disorders through inhibition of mTOR function. In addition, the present invention provides methods and compositions that utilize mTOR inhibiting agents (e.g., rapamycin) in the detecting, preventing, treating, and empirical investigating of seizures and seizure related disorders.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF MICHIGAN1600 HURON PARKWAY 2ND FLOOR OFFICE OF TECHNOLOGY TRANSFER ANN ARBOR MI 48109-2590
CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER3333 BURNET AVENUE CINCINNATI OH 45229-3039

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Franz, David Springboro, OH 5 59
Guan, Kun-Liang Ann Arbor, MI 10 108

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