Abc Transporter Inhibitor

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20080167444A1
SERIAL NO

10591332

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Abstract

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It is an object of the present invention to provide an ABC transporter inhibitor whereby the multi-drug resistance against anticancer drugs caused by amplification and expression of MDR1 gene, which is the most serious problem in chemotherapy for cancer, or the resistance against antifungal agents in mycotic diseases can be overcome. The present invention relates to an ABC transporter inhibitor containing enniatin or its analog as the active ingredient. The ABC transporter inhibitor of the present invention, being capable of inhibiting transport/excretion of a drug, especially an anticancer drug or an antifungal agent, from inside to outside of cells, is useful in preventing, suppressing, or inhibiting acquisition of resistance against various drugs.

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Patent Owner(s)

Patent OwnerAddress
SUNTORY LIMITED1-40 DOJIMAHAMA 2-CHOME KITA-KU OSAKA-SHI OSAKA 530-8203

International Classification(s)

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  • 2005 Application Filing Year
  • C07K Class
  • 2011 Applications Filed
  • 601 Patents Issued To-Date
  • 29.89 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200520062007200820092010201120122013201420152016201720182019202020210255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hiraga, Kazumi Uji, JP 12 9
Oda, Kohei Izumi, JP 35 117

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges483771235230963321901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0255075100125150175200225250275300325350375400

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