Fusion Proteins and Methods for Determining Protein-Protein-Interactions in Living Cells and Cell Lysates, Nucleic Acids Encoding these Fusion Proteins, as well as Vectors and Kits Containing These

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United States of America Patent

APP PUB NO 20080161199A1
SERIAL NO

11793161

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Abstract

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The present invention refers to inventive fusion proteins, to a method for detecting protein-protein-interactions in living cells and cell lysates using these inventive fusion proteins. The present invention also refers to a screening method for identifying compounds suitable to modify, i.e. inhibit or enhance, protein-protein-interaction using these fusion proteins. Additionally a method for detecting cells is disclosed comprising an unknown protein that interacts with a known protein. Along with the inventive fusion proteins used for these methods encoding nucleic acids, corresponding vectors and host cells transfected accordingly are disclosed herewith.

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Patent Owner(s)

Patent OwnerAddress
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH)INGOLSTADTER LANDSTRASSE 1 NEUHERBERG 85764

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brack-Werner, Ruth Munich, DE 5 11
Brebeck, Andrea Hoehenkirchen-Siegertsbrunn, DE 1 0
Wolff, Horst Munich, DE 13 88
Ziegler, Manja Munich, DE 1 0

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