Pharmaceutical Compositions Containing Biophosphonate for Improving Oral Absorption
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United States of America Patent
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Issued Date -
Jun 26, 2008
app pub date -
Jan 3, 2006
filing date -
Jan 31, 2005
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Abandoned
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Abstract
Provided is a pharmaceutical composition having improved oral absorption of a bisphosphonate drug, comprising at least one active substance selected from bisphosphonate drugs having non-permeability to a lipid biomembrane due to ionization and high water-solubility in vivo and having bioavailability of less than 10%, and at least one selected from biocompatible water-soluble chitosan, as essential ingredients.
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