Bicyclic and Tricyclic Heteroaromatic Compounds
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United States of America Patent
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Issued Date -
Jun 19, 2008
app pub date -
Feb 4, 2008
filing date -
Nov 12, 1999
priority date (Note) -
Abandoned
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Abstract
Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof, wherein W, Q, X, X.sub.1, Y and Z are as defined herein. These compounds bind with high selectivity and/or high affinity to the benzodiazepine site of GABA.sub.A receptors and are therefore useful in the treatment of central nervous system (CNS) diseases and as probes for the localization of GABA.sub.A receptors in tissue samples. Also disclosed are intermediates useful in the preparation of these compounds.
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