Compositions and Methods for the Treatment and Prevention of Neoplastic Disorders

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20080145313A1
SERIAL NO

11847733

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compositions for the treatment and/or prevention of cancer in a mammal by means of RNA interference are provided, together with methods for the use of such compositions. The compositions comprise a small interfering nucleic acid molecule (siNA) that suppresses expression of a target gene that: (a) is involved in an energy metabolism pathway, such as the glycolysis pathway, within a tumor cell; (b) is involved in the biosynthesis of nucleotides, in glycogen metabolism or is an electron carrier that works with ATP to provide metabolic energy; or (c) is involved in transport of sugars, amino acids, and/or water-soluble vitamins, control of intercellular pH, or drug transport within a tumor cell.

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Patent Owner(s)

Patent OwnerAddress
GENESIS RESEARCH AND DEVELOPMENT CORPORATION LTDONE FOX STREET AUCKLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Havukkala, llkka J Auckland, NZ 1 4
Hiyama, Jun Auckland, NZ 4 27
Lasham, Annette Auckland, NZ 9 55
Reid, Glen Auckland, NZ 13 84
Visser, Elizabeth S Auckland, NZ 1 4
Watson, James D Auckland, NZ 49 810

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