Preparation of nucleosides ribofuranosyl pyrimidines

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United States of America Patent

APP PUB NO 20080139802A1
SERIAL NO

11973748

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Abstract

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The present process provides an improved method for converting 2'-deoxy-2'-fluoro-2'-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds which are useful for the synthesis of nucleosides and improved processes for the synthesis of the D-ribonolactone compounds.

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Patent Owner(s)

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PHARMASSET INCC/O GILEAD SCIENCES INC 333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Axt, Steven D Menlo Park, CA 7 91
Chun, Byoung-Kwon Robbinsville, NJ 45 1248
Jin, Qingwu San Jose, CA 14 86
Rachakonda, Suguna Robbinsville, NJ 22 863
Ross, Bruce Plainsboro, NJ 28 811
Sarma, Keshab Sunnyvale, CA 28 765
Vitale, Justin San Mateo, CA 7 85
Zhu, Jiang Cupertino, CA 283 2679

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