DRUG COMBINATION FOR HYPERTENSIVE DISORDERS
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United States of America Patent
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app pub date -
Dec 11, 2007
filing date -
Dec 12, 2006
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Abstract
Therapeutic combinations and pharmaceutical compositions are provided comprising ambrisentan and an inhibitor of renin activity or release. Such combinations and compositions are useful to treat hypertensive disorders, particularly pulmonary hypertension conditions such as pulmonary arterial hypertension, to prevent cardiovascular adverse events related thereto, to enhance pulmonary function and to extend time to clinical worsening in a subject having a pulmonary hypertension condition.
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