Microgravity bioreactor systems for production of bioactive compounds and biological macromolecules
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United States of America Patent
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Issued Date -
Jun 12, 2008
app pub date -
Dec 8, 2006
filing date -
Dec 8, 2006
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Abandoned
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Abstract
The present invention relates to compositions and methods of plant, fungal and bacterial cell culture that can be effectively utilized for three-dimensional plant, fungal, and bacterial cell growth and production of bioactive compounds of interest. The culture methods employ a microgravity environment such that rapid establishment and expansion of cells into tissue constructs occurs influencing expression of biological macromolecules and biopharmaceuticals. The present invention is further directed to a method for the in vitro cultivation of plant, fungal, and bacterial cells in a liquid nutrient medium in modeled microgravity with potential for large scale manipulations.
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