MODULATION OF POLYSIALYLATED NEURAL ADHESION MOLECULES (PSA-NCAM) AS A REGULATOR OF OCULAR DISEASE
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United States of America Patent
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Issued Date -
Jun 5, 2008
app pub date -
Nov 29, 2007
filing date -
Dec 1, 2006
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Abandoned
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Abstract
A method of treating dry eye or dry eye symptom includes topically administering a formulation to the eye. The formulation includes an ophthalmically acceptable carrier and a pharmaceutically effective amount of a positive modulator of PSA-NCAM. The administered formulation treats dry eye or dry eye symptoms. A method of stimulating the expression of PSA-NCAM in neural beds of an eye includes topically administering a formulation to the eye. The formulation includes an ophthalmically acceptable carrier and a pharmaceutically effective amount of a positive modulator of PSA-NCAM. The administered formulation may stimulate the expression of PSA-NCAM in the neural beds of the eye. A formulation includes an ophthalmically acceptable carrier and a therapeutically effective amount of a positive modulator of polysialic acid-neural cell adhesion molecule (PSA-NCAM).
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