Unique Integrin Binding Site in Connective Tissue Growth Factor
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United States of America Patent
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Issued Date -
May 29, 2008
app pub date -
Nov 15, 2007
filing date -
Sep 29, 2003
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Abandoned
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Abstract
The invention relates to a connective tissue growth factor peptide that encompasses a CTGF binding site for an integrin such as .alpha..sub.v.beta..sub.3 or .alpha..sub.5.beta..sub.1 and uses therefor. The invention also relates to agonists and inhibitors of the CTGF-integrin binding and methods of treating and preventing CTGF-related disorders.
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