Method for kinetic characterization from temporal image sequence
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United States of America Patent
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Issued Date -
May 22, 2008
app pub date -
Nov 22, 2006
filing date -
Nov 22, 2006
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Abandoned
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Abstract
A computerized derivable kinetic characterization measurement method for live cell kinetic characterization inputs kinetic recognition data for a plurality of time frames. A single cell measurement step is performed using the kinetic recognition data for a plurality of time frames to generate single cell feature for a plurality of time frames output. The single cell feature includes cell morphological profiling feature. A kinetic measurement step uses the single cell feature for a plurality of time frames to generate kinetic feature output. A trajectory measurement step uses the single cell feature for a plurality of time frames and the kinetic feature to generate trajectory feature output. An interval measurement step uses the kinetic feature to generate interval feature output. A cell state classifier step uses the interval feature to generate cell state output. A state based measurement uses the single cell feature, the kinetic feature and the cell state to generate state based feature output.
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