Method For Detecting Methylation In Genes And Method For Examining Neoplasm Through Detecting Methylation In Genes

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20080118926A1
SERIAL NO

11793030

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

An object of the present invention is to provide a method for detecting methylation in genes contained in a biological sample in a simple and economical manner. Further object of the present invention is to provide an accurate and good sensitivity examination method for a case the neoplasm is assayed using method for detecting methylation in DNAs. The biological sample is supplied with a polysaccharide before it is processed with a bisulfite in order to detect methylation in genes, allowing processing with a bisulfite thereafter, and thereby to allow detection of methylated cytosine which has not been modified to convert into uracil, even if the sample is not supplied with protein denaturing agent and the DNA is not purified to detect. Further, the present invention can examine neoplasm more accurately, because it detects methylation on a plurality of genes contained in the biological sample to calculate the total of their respective methylation values.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
BIO-DIXAM LLCOKAYAMA-SHI OKAYAMA 700-0927

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsubara, Nagahide Okayama, JP 3 11
Nagasaka, Takeshi Aichi, JP 32 372
Tanaka, Noriaki Okayama, JP 84 532

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation