Modified Release of Compositions Containing a Combination of Carbidopa, Levodopa and Entacapone
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United States of America Patent
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Issued Date -
May 22, 2008
app pub date -
Jun 5, 2006
filing date -
Nov 2, 1998
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Abandoned
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Abstract
The invention relates to a multiparticulate modified release composition that, upon administration to a patient, delivers a combination of carbidopa, levodopa and entacapone in a bimodal, multimodal or continuous manner. The multiparticulate modified release composition comprises a first component and at least one subsequent component, the first component comprising a first population of active ingredient containing particles and the at least one subsequent component comprising a second population of active ingredient containing particles. The invention also relates to a solid oral dosage form containing such a multiparticulate modified release composition, and to a method for the treatment of Parkinson's disease.
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