Cell density fitting equation
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United States of America Patent
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Issued Date -
May 15, 2008
app pub date -
Feb 6, 2007
filing date -
Nov 10, 2006
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Abandoned
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Abstract
A method for converting non-linear optical loss readings in a bioreactor process vessel into process parameter units by applying a curve fitting algorithm to the fitting function represented by the empirical equation: yol = A + B ( 1 - - x PU C ) + D x PU wherein x.sub.PU is in the process units (PU), y.sub.ol is optical loss in the chosen units, A is the offset, D is the absorption coefficient, B is the effective scattering coefficient, and C is the scattering constant. The preferred fitting algorithm is Levenberg-Marquardt.
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