Methods and Compositions for High Sensitivity Fluorescent Mutation Detection with Mismatch Cutting Dna Endonucleases
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United States of America Patent
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Issued Date -
May 15, 2008
app pub date -
Nov 14, 2005
filing date -
Nov 12, 2004
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Abandoned
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Abstract
Methods and kits are provided with DNA substrates having a fluorescent label positioned at a nucleotide internal from its 5' end for use with CEL nuclease to determine whether a DNA sequence contains mutations or polymorphic changes.
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