METHOD AND APPARATUS FOR ANALYTE MEASUREMENTS IN THE PRESENCE OF INTERFERENTS
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United States of America Patent
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Issued Date -
May 15, 2008
app pub date -
Aug 15, 2007
filing date -
Aug 15, 2006
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Abandoned
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Abstract
Method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement. The method reduces the error in the analyte concentration in the presence of interferents. The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations. From a sample measurement, which may or may not be one of the population, interferents likely to be present are identified, and a calibration coefficient is calculated. The calibration coefficient may be applied to the measurement to estimate the analyte concentration. In some implementations, the calibration coefficient may be determined as a weighted average of single interferent calibration coefficients. In some embodiments, the sample measurement includes a spectroscopic measurement.
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