Peptide Nucleic Acid Conjugates and Uses Thereof
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United States of America Patent
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Issued Date -
May 8, 2008
app pub date -
Oct 15, 2004
filing date -
Oct 17, 2003
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Abandoned
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Abstract
The invention provides a triphenylphosphonium peptide nucleic acid conjugate. The conjugate comprises a peptide nucleic acid linked via a disulfide bond, to a triphenylphosphonium group. Conjugates of the invention can be used to deliver PNA oligomers across the plasma membrane into cells.
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