Antibodies against inducible TH2 cell factors
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United States of America Patent
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Issued Date -
Apr 24, 2008
app pub date -
Dec 20, 2006
filing date -
May 1, 1999
priority date (Note) -
Abandoned
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Abstract
A novel TH2 associated gene that is induced by IL-9 has been identified and isolated, thereby providing a therapeutic target for IL-9 mediated diseases such as atopic allergy and asthma-related disorders. The invention also includes methods for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders, methods for diagnosing susceptibility to, and assessing treatment of atopic allergy or asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein. The use of this protein as a therapeutic agent for the treatment of autoimmune diseases is also indicated.
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