Assays For Superantigens
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United States of America Patent
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Issued Date -
Apr 17, 2008
app pub date -
Oct 31, 2005
filing date -
Dec 16, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides a superantigen quality control assay, particularly for SEA-E120, comprising incubating a standard amount of a superantigen-containing test sample with a standard amount of a soluble TCR which binds the superantigen, separating unbound TCR from the resultant superantigen/TCR-containing sample, quantifying the TCR bound in that sample, and comparing that result with a reference result characterising a control superantigen-containing sample. Also provided are soluble TCRs useful as reagents in said assay.
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