Antibody

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United States of America Patent

APP PUB NO 20080085241A1
SERIAL NO

11835010

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides the amino acid and nucleic acid sequences of heavy and light chain complementarity determining regions of tumor specific binding proteins. In particular, the present invention provides an antibody which comprises at least one heavy chain variable region (VH) that comprises three CDRs, wherein said heavy chain variable region comprises: (i) a heavy chain CDR1 domain that comprises the amino acid sequence SYSMN (SEQ ID NO. 35), (ii) a heavy chain CDR2 domain that comprises the amino acid sequence SISSSSSYIYYADSVKG (SEQ ID NO. 39), and (iii) a heavy chain CDR3 domain that comprises the amino acid sequence SSGWYDGEFDP (SEQ ID NO: 40), wherein said antibody is capable of specifically binding to CD98hc or fragments of CD98hc.

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Patent Owner(s)

Patent OwnerAddress
VIVENTIA BIOTECH INC5060 SPECTRUM WAY SUITE 405 MISSISSAUGA ONTARIO L4W 5N5
AFFITECH AS0371 OSLO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chahal, Francina Celestina Winnipeg, CA 1 5
Cizeau, Jeannick Paul Winnipeg, CA 1 5
Stassar, Marike Josee Janneke Gertrude Baerums Verk, NO 1 5

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