SMG-1 BINDING PROTEIN AND SCREENING METHOD FOR SUBSTANCES THAT CAN REGULATE THE ACTIVITY THEREOF
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United States of America Patent
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app pub date -
Jun 21, 2007
filing date -
Sep 5, 2002
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Abstract
A novel polypeptide binding to SMG-1, a polynucleotide encoding the same, and a system for screening a substance which artificially modifies an MRNA surveillance mechanism, are disclosed. The polypeptide has an activity of binding to SMG-1, an activity of being phosphorylated by SMG-1, and an activity of modifying SMG-1 activities through these activities.
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