UTILITY OF HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN IN DIAGNOSIS AND TREATMENT OF CANCER

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United States of America Patent

APP PUB NO 20080076727A1
SERIAL NO

11693678

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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HMW-MAA antibody cocktails and their uses in detecting cancer and isolating cancer cells are disclosed. Also disclosed are methods of detecting cancer based on the presence of an HMW-MAA genomic sequence in circulating DNA, as well as the increased expression of the HMW-MAA gene and the reduced methylation of the HMW-MAA gene promoter in tissues and circulating cells.

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Patent Owner(s)

Patent OwnerAddress
JOHN WAYNE CANCER INSTITUTE2200 SANTA MONICA BOULEVARD ST JOHN SOUTH HEALTH CENTER SANTA MONICA CA 90404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ferrone, Soldano Pittsburgh, PA 43 164
Goto, Yasufumi Matsumoto, JP 5 5
Hoon, Dave SB Los Angeles, CA 48 292
Kitago, Minoru Santa Monica, CA 8 8

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