Polycationic sterol derivatives as transfection agents

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United States of America Patent

SERIAL NO

11868184

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Abstract

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A method for treating genetic disorders or conditions or diseases in patients in need of such treatments. The method includes administering an effective amount of a compound comprising a cholesterol group or derivative thereof having linked thereto a head group. The head group is more positive than the heat group of DC-Chol. The heat group may be a straight chain polymeric group having two or more amine groups separated by an ethylene group.

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Patent Owner(s)

Patent OwnerAddress
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINEUNIVERSITY OF LONDON LONDON SW7 2AZ UNITED KINGDOM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cooper, Robert G London, GB 5 11
Etheridge, Christopher J London, GB 3 4
Miller, Andrew D London, GB 4 20

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