Piperidine Derivative or Pharmaceutically Acceptable Salt Thereof

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United States of America Patent

APP PUB NO 20080070898A1
SERIAL NO

11661446

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The piperidine derivative of the present invention in which the 4-position of the piperidine ring is bonded, via vinylene, to a mono-substituted (--R.sup.1) or unsubstituted benzene ring and the 1-position of the piperidine ring has an acyl group [--C(.dbd.O)--R.sup.4], or a pharmaceutically acceptable salt thereof has an excellent sodium channel inhibition action and an excellent analgesic action and shows a high analgesic effect particularly to neurogenic pain. The present compound is useful as a sodium channel inhibitor of low side effect

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INC5-1 NIHONBASHI-HONCHO 2 -CHOME CHUO-KU TOKYO 103-8411 ?103-8411
KOTOBUKI PHARMACEUTICAL CO LTDHANISHINA-GUN NAGANO 389-0697

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujiyasu, Jiro Tokyo, JP 10 49
Iwai, Yoshinori Nagano, JP 12 210
Kikuchi, Kazumi Tokyo, JP 6 31
Nagakura, Yukinori Tokyo, JP 7 32
Sonegawa, Motoharu Nagano, JP 6 35
Tokuzaki, Kazuo Nagano, JP 6 86
Tomiyama, Hiroshi Nagano, JP 38 811
Watanabe, Toshihiro Tokyo, JP 66 318

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