INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY
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United States of America Patent
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Issued Date -
Mar 13, 2008
app pub date -
Mar 22, 2007
filing date -
Mar 22, 2006
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Abstract
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
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