GENE TRANSFER METHODS

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United States of America Patent

SERIAL NO

11829313

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Abstract

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Improved methods for transferring a gene into target cells by using a retrovirus, wherein the gene transfer efficiency is improved and the target cells are efficiently transformed by binding the retrovirus to a functional substance which is immobilized on as carrier and having an activity of binding to retroviruses followed by washing; using an antibody capable of specifically recognizing cells, laminin or mannose-rich type sugar chain as a substance having an activity of binding to the target cells; pre-treating the target cells so as to inactivate transferring receptor, or introducing a new functional group into the functional substance.

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Patent Owner(s)

Patent OwnerAddress
TAKARA SHUZO CO LTDKYOTO-SHI KYOTO 612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asada, Kiyozo Koka-gun, JP 70 521
Chono, Hideto Moriyama-shi, JP 23 62
Fujinaga, Kei Otsu-shi, JP 8 43
Hashino, Kimikazu Osaka, JP 15 97
Kato, Ikunoshin Uji-shi, JP 314 1701
Konishi, Haruko Kyoto-shi, JP 4 15
Miyamura, Tsuyoshi Kusatsu-shi, JP 164 608
Morishita, Mio Otsu-shi, JP 11 93
Sano, Mutsumi Otsu-shi, JP 15 101
UENO, Mitsuhiro Kasatsu-shi, JP 24 180
Yoshioka, Hirofumi Kasatsu-shi, JP 12 84

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