Method for Detection of Conformational Change of a Protein Immobilized on a Substrate
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United States of America Patent
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Issued Date -
Feb 14, 2008
app pub date -
Sep 21, 2005
filing date -
Sep 22, 2004
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Abandoned
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Abstract
This invention provides a method for detection of conformational change of a protein immobilized on a substrate. In concrete, the method comprises, forming a sample film comprising a protein immobilized on a substrate, adding a substance to be detected for its activity to affect to the conformational change of the protein onto the sample film, and detecting the conformational change of the protein. The method enables to measure conformational change of a protein with immobilized state, using minute amount of protein in a short period for a number of samples in a short period all at once, rapidly and simply.
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