Prevention of damage in hippocampus of fetus/newborn infant due to maternal gestational hypertension

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20080038288A1
SERIAL NO

11503172

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Abstract

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The present invention provides a method for preventing or ameliorating neural damage in a mammalian fetus or a newborn infant, which is caused by maternal gestational hypertension (GH). The method includes orally administering germination activated sporoderm-broken Ganoderma lucidum spores ('GLSs') to a pregnant mammal having GH. The neural damage includes a decrease in hippocampal cell proliferation and neuron number. The present invention further provides a method for preventing or ameliorating the increased expression of hippocampal hypoxia inducible factor (HIF-1a) and vascular endothelial growth factor (VEGF) in a mammalian embryo caused by maternal GH.

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Patent Owner(s)

Patent OwnerAddress
KINDWAY INTERNATIONA LIMITED22/F LIPO LEIGHTON TOWER 103 LEIGHTON ROAD CAUSEWAY BAY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chung, Chee-Keung Kowloon, HK 15 16
Zeng, Yuan-Shan Guangzhou, CN 3 3

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