High dose orally dissolvable/disintegrable lyophilized dosage form
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United States of America Patent
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N/A
Issued Date -
Feb 7, 2008
app pub date -
Jul 23, 2007
filing date -
Jul 24, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides an orally dissolvable/disintegrable, lyophilized dosage form including a protected granulate comprising an active ingredient and a protective granulation binder, which substantially protects the form and/or attributes of a granulate and/or active ingredient, and participates in masking bad tasting active ingredients, such as sulfur-containing materials, and a matrix, and a method for making same. There is also provided a method of treating a patient using any orally dissolvable/disintegrable lyophilized dosage form comprising the steps of placing the dosage form in the mouth of a patient in need of treatment, allowing the dosage form to disintegrate/dissolve sufficiently to allow it, and in particular, the protected granulate, to be swallowed as a solution, suspension or slurry, and swallowing the at least partially disintegrated/dissolved dosage form.
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