Methods and systems for toxin delivery to the nasal cavity
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United States of America Patent
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Feb 2, 2010
Grant Date -
Jan 24, 2008
app pub date -
May 18, 2007
filing date -
Jul 22, 2005
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Abstract
Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity.
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