Medicine Capable of Inhibiting Activation of Transcription Factor Klf5
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United States of America Patent
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Issued Date -
Jan 24, 2008
app pub date -
Feb 24, 2005
filing date -
Feb 25, 2004
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Abstract
A medicament having an action of inhibiting activation of transcription factor KLF5 and thus inhibiting vascular remodeling and arteriosclerosis, which comprises an acyclic polyprenyl compound (e.g., polyprenylcarboxylic acid such as 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentanoic acid and the like) as an active ingredient.
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