Pharmaceutical Composition for Rectal, or Vaginal Application, Method of Manufacturing and Use as Medicament Thereof
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United States of America Patent
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Issued Date -
Jan 10, 2008
app pub date -
Sep 7, 2005
filing date -
Sep 8, 2004
priority date (Note) -
Abandoned
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Abstract
A pharmaceutical composition for rectal or vaginal application, characterized in that it contains as active substance the platinum complex of general formula wherein A each independently is an --NH.sub.3 group or an amino group containing 1 to 18 carbon atoms, B each independently is a halogen atom, a hydroxy group or a --O--C(O)--R group wherein R each independently is hydrogen atom or an alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy group containing 1 to 10 carbon atoms or functional derivatives of these groups, and X each independently is a halogen atom or a monocarboxylate group containing 1 to 20 carbon atoms, or X together form a dicarboxylate group containing 2 to 20 carbon atoms, and a hydrophilic gel-forming base, comprising gelatin, water and glycerol.
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